Intangia.
Indication Atlas
09 Jul 2026

851 indications, tiered by therapeutic opportunity.

Every disease in our resolved catalogue that carries an active drug programme in our data — 851 indications — scored on an opportunity index (unmet need + druggable, genetically-validated biology + pipeline momentum + research), banded into Tier 1/2/3, and flagged for blue-sky white-space where the opportunity is high but the field is uncrowded. Each indication carries its own target-tier profile, linking the view to a target-tiering lens.

851 indications851 with in-house assets16 therapeutic areas350 with no approved therapy

851 scored today — a slice of the resolver's reach

This view ranks the 851 indications that already carry active drug programmes in our data. The same pipeline extends much further: our resolver has mapped 25,088 disease concepts, 16,698 of them high-confidence, and 7,517 already carry drug-evidence — the scored universe grows as more evidence is ingested and the commercial axis comes online.

851
Scored & ranked today
Evidence-backed indications with active programmes
7,517
Already carry drug-evidence
Near-term expansion of the scored set
16,698
High-confidence diseases
Auto-resolved, high-confidence disease concepts
25,088
Total resolved concepts
The full mapped catalogue behind this work

One index, six axes

Each disease scores 0–10 on an opportunity index — a weighted mean of six axes that together balance how under-served a disease is against how actionable it looks. Every number is computed from our own enrichment plus the public Open Targets Platform.

Therapy gap · 28%

Is there an effective therapy?

Combined clinical landscape (Open Targets + our own drug-evidence): candidates but no approval score by most advanced phase; approvals pull it down.

Tractability & genetics · 20%

Is the biology druggable and validated?

Open Targets genetic-association strength and per-target druggability (tractable modalities), blended with our own druggable-genome tier (T1/T2) for the disease's pipeline targets.

Prevalence / burden · 15%

How many are affected?

Orphanet prevalence class as a population-burden proxy, ordinal from ultra-rare to common.

Research activity · 15%

How well studied?

Open Targets literature co-occurrence volume (log-scaled) — a proxy for scientific attention and validation.

Pipeline momentum 12% programmes advancing vs terminated (where trial status is known) Pipeline whitespace 10% fewer active programmes scores higher Weights Therapy gap 28% · Tractability & genetics 20% · Prevalence / burden 15% · Research activity 15% · Pipeline momentum 12% · Pipeline whitespace 10%
Tiers indications band by opportunity index — Tier 1 (top ~20%), Tier 2 (next ~40%), Tier 3 (rest), mirroring a target-tiering system White-space a separate lens from competitive crowdedness (programme + sponsor counts); ★ blue-sky = Tier 1 and uncrowded Target tiers each indication carries its pipeline targets' druggability tiers (T1/T2/non-coding) — the bridge to the target-tiering framework

What this index does and does not include

The index deliberately balances two pulls: whitespace rewards diseases with few competing programmes, while momentum and research reward activity and validation — so a disease that is both under-served and biologically actionable rises highest. Gap and context axes (therapy, prevalence, whitespace, momentum) renormalise when a signal is missing. Tractability and research are positive-evidence axes: where no Open Targets node or druggable target resolves, they are floored rather than dropped, so an unstudied disease with no demonstrable druggable biology is not rewarded for the gap in our knowledge. Population burden rests on Orphanet alone (rare-disease-heavy); a commercial/deal axis is a planned addition. A research signal, not clinical guidance.

Where the 851 indications sit

Distribution across our 16-value therapeutic-area vocabulary. Counts sum to more than 851 because many diseases carry more than one area.

Oncology183
Infectious Disease118
Rare/Genetic86
Immunology & Inflammation80
Gastroenterology69
Neurology/CNS64
Metabolic & Endocrine60
Cardiovascular59
Women's & Reproductive Health49
Respiratory48
Musculoskeletal41
Hematology36
Dermatology32
Nephrology/Urology30
Psychiatry24
Ophthalmology20

The strongest opportunities, in detail

The top 12 by opportunity index. Click any card (or any table row below) to open its full profile — the six-axis breakdown with the evidence behind each score, every programme and target we hold, and source links.

001
8.04Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 826
Score axes · 0–10
Unmet9
Tract7.15
Prev
Res6.8
Mom
Space9.01
#1T1

Subacute necrotizing encephalomyopathy

Neurology/CNS

No approved therapy yet; 1 programme in development. Top associated targets: MT-ND5, MT-ND1, MT-ND4, MT-ND6.

Programmes in our data
ModalitySmall Molecule(1)
Assets (1)SONLICROMANOL
Statusfurthest phase not recorded · 1 sponsor(s)
002
7.71Opportunity index · 0–10
Open Targets drugs 2 · approved 0 Genetic targets 1890
Score axes · 0–10
Unmet7
Tract6.95
Prev
Res9.86
Mom
Space8.01
#2T1

Drug Abuse

No approved therapy yet; 3 programmes in development, furthest at Phase 2. Top associated targets: ADH1B, GABRA2, GABRB2, GABRB1.

Programmes in our data
ModalitySmall Molecule(3)
Assets (3)METFORMIN HYDROCHLORIDE; ACYCLOVIR; ACYCLOVIR SODIUM
Statusfurthest phase not recorded · 2 sponsor(s)
003
7.4Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 1006
Score axes · 0–10
Unmet9
Tract4.17
Prev
Res7.66
Mom
Space9.01
#3T1

Skin ulcer due to varicose veins

Cardiovascular

No approved therapy yet; 1 programme in development. Top associated targets: ADRA1B, ADRA1D, ADRA1A, SCN10A.

Programmes in our data
MoAmodulator(1)
TargetsABCB5-positive mesenchymal stromal cells
Assets (1)Skin-derived ABCB5-positive Mesenchymal Stem cells
Statusfurthest phase not recorded · 1 sponsor(s)
004
7.32Opportunity index · 0–10
Open Targets drugs 2 · approved 0 Genetic targets 4328
Score axes · 0–10
Unmet8.5
Tract4.79
Prev
Res7.76
Mom
Space8.43
#4T1

Hypertension-Associated Pregnancy Disorder

CardiovascularWomen's & Reproductive Health

No approved therapy yet; 2 programmes in development, furthest at Preclinical / IND. Top associated targets: SLC12A3, CORIN, STOX1, FTO.

Programmes in our data
ModalitySmall Molecule(1)
Assets (1)PROGESTERONE
Statusfurthest phase not recorded · 1 sponsor(s)
005
7.31Opportunity index · 0–10
Open Targets drugs 1 · approved 0 Genetic targets 6818
Score axes · 0–10
Unmet6
Tract6.31
Prev
Res8.19
Mom10
Space8.43
#5T1

mitochondrial respiratory chain disorder

Respiratory

No approved therapy yet; 2 programmes in development, furthest at Phase 3. Top associated targets: POLG, AFG3L2, TWNK, RRM2B.

Programmes in our data
ModalitySmall Molecule(4)
MoAinhibitor(1); modulator(1)
TargetsMicrosomal Prostaglandin E Synthase-1; NAD(P)H quinone dehydrogenase 1
Assets (2)SONLICROMANOL; VATIQUINONE
Statusfurthest phase Phase 3 · 2 sponsor(s)
006
7.24Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 837
Score axes · 0–10
Unmet8.5
Tract5.72
Prev
Res5.73
Mom
Space9.01
#6T1

Progressive hearing loss

No approved therapy yet; 1 programme in development, furthest at Preclinical / IND. Top associated targets: GJB2, MYO7A, MYH9, KCNQ4.

Programmes in our data
ModalityGene Therapy(1)
MoAmodulator(1)
TargetsGJB2
Assets (1)GJB2-GT
Statusfurthest phase Preclinical / IND · 1 sponsor(s)
007
7.1Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 1790
Score axes · 0–10
Unmet9
Tract4.03
Prev
Res6.36
Mom
Space9.01
#7T1

Rare epilepsy

Neurology/CNSRare/Genetic

No approved therapy yet; 1 programme in development. Top associated targets: CSTB, NHLRC1, EPM2A, KCTD7.

Programmes in our data
ModalitySmall Molecule(1)
MoAmodulator(1)
TargetsKv3.1/3.2 potassium channels
Assets (1)AUT00206 x AUT00201
Statusfurthest phase not recorded · 1 sponsor(s)
008
7.1Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 0
Score axes · 0–10
Unmet8.5
Tract8
Prev
Res2
Mom
Space9.01
#8T1

Extensively Drug-Resistant Tuberculosis

OncologyInfectious Disease

No approved therapy yet; 1 programme in development, furthest at Preclinical / IND.

Programmes in our data
ModalitySmall Molecule(1)
MoAinhibitor(6); modulator(1)
TargetsEGFR; cereblon; BTK
Assets (1)AEV40154
Statusfurthest phase Preclinical / IND · 2 sponsor(s)
009
7.07Opportunity index · 0–10
Open Targets drugs 1 · approved 0 Genetic targets 1510
Score axes · 0–10
Unmet7
Tract5.94
Prev7
Res7.48
Mom
Space9.01
#9T1

arrhythmogenic right ventricular cardiomyopathy

Cardiovascular1-5 / 10 000

No approved therapy yet; 1 programme in development, furthest at Phase 2. Top associated targets: RYR2, DSG2, JUP, DSP.

Programmes in our data
MoAgene therapy(1)
Targetsplakophilin 2
Assets (1)RP-A601
Statusfurthest phase Phase 1 · 1 sponsor(s)
010
7.03Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 0
Score axes · 0–10
Unmet8
Tract6.67
Prev
Res2
Mom10
Space9.01
#10T1

Recurrent Platinum-Resistant Ovarian Carcinoma

OncologyNeurology/CNSWomen's & Reproductive Health

No approved therapy yet; 1 programme in development, furthest at Phase 1.

Programmes in our data
MoAcell therapy(3)
TargetsB7-H3
Assets (1)Autologous Anti-B7-H3 CAR T Cells
Statusfurthest phase Phase 1 · 1 sponsor(s)
011
7.02Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 0
Score axes · 0–10
Unmet9
Tract7.5
Prev
Res2
Mom
Space8.01
#11T1

High Grade B-Cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements

OncologyMusculoskeletal

No approved therapy yet; 3 programmes in development.

Programmes in our data
ModalitySmall Molecule(1); Antibody(1)
MoAinhibitor(2)
TargetsCDK9; programmed cell death 1
Assets (3)ENITOCICLIB x PEMBROLIZUMAB; ENITOCICLIB; PEMBROLIZUMAB
Statusfurthest phase not recorded · 1 sponsor(s)
012
7.02Opportunity index · 0–10
Open Targets drugs 0 · approved 0 Genetic targets 0
Score axes · 0–10
Unmet9
Tract7.5
Prev
Res2
Mom
Space8.01
#12T1

Primary combined hyperlipidemia

Metabolic & EndocrineRare/Genetic

No approved therapy yet; 3 programmes in development.

Programmes in our data
ModalityCombination(1); Antibody(1); Small Molecule(1)
MoAinhibitor(2)
Targetsproprotein convertase subtilisin/kexin type 9; 3-hydroxy-3-methylglutaryl-CoA reductase
Assets (3)Evolocumab x atorvastatin; EVOLOCUMAB; ATORVASTATIN
Statusfurthest phase not recorded · 1 sponsor(s)

All 851 scored indications, tiered by opportunity

Sorted by index descending and banded into tiers (T1 top ~20%, T2 next ~40%, T3 the rest). Bars show five axes (0–10): unmet need, tractability & genetics, research, momentum and white-space. Click any row for the full profile. Showing the top 50.

#TierIndicationAreaIndexUnmetTract.ResearchMomentumWhitespaceAssetsLead
1T1 Subacute necrotizing encephalomyopathyNeurology/CNS8.0497.156.88.251SONLICROMANOL
2T1 Drug Abuse7.7176.959.866.823METFORMIN HYDROCHLORIDE
3T1 Skin ulcer due to varicose veinsCardiovascular7.494.177.668.251Skin-derived ABCB5-positive Mesenchymal Stem cells
4T1 Hypertension-Associated Pregnancy DisorderCardiovascular7.328.54.797.767.671PROGESTERONE
5T1 mitochondrial respiratory chain disorderRespiratory7.3166.318.19107.232SONLICROMANOL
6T1 Progressive hearing loss7.248.55.725.738.251GJB2-GT
7T1 Rare epilepsyNeurology/CNS7.194.036.368.251AUT00206 x AUT00201
8T1 Extensively Drug-Resistant TuberculosisOncology7.18.5827.811AEV40154
9T1 arrhythmogenic right ventricular cardiomyopathCardiovascular7.0775.947.488.251RP-A601
10T1 Recurrent Platinum-Resistant Ovarian CarcinomaOncology7.0386.672108.251Autologous Anti-B7-H3 CAR T Cells
11T1 High Grade B-Cell Lymphoma with MYC and BCL2 aOncology7.0297.527.263ENITOCICLIB x PEMBROLIZUMAB
12T1 Primary combined hyperlipidemiaMetabolic & Endocrine7.0297.527.263Evolocumab x atorvastatin
13T1 Recurrent Liposarcoma7.01782108.251BTX-A51
14T1 Acute phototoxic reaction6.998.55.664.997.671PRÉNUMBRA®
15T1 Congenital anomalies of kidney and urinary traNephrology/Urology6.9493.426.428.251REGEND 003
16T1Triple hit lymphomaOncology6.9397.6725.837IDP-121
17T1 Bipolar I disorder, most recent episode depresPsychiatry6.9296.6728.251ARIPIPRAZOLE
18T1 Decompensated cirrhosis of liverGastroenterology6.9296.6728.251EMRICASAN
19T1 Malignant lymphoma of extranodal AND/OR solid Oncology6.9296.6728.251CZ48
20T1 Non-Functioning Lung Neuroendocrine TumorOncology6.9296.6728.251SPARTALIZUMAB
21T1 Schizophrenic prodromePsychiatry6.9296.6728.251ASPIRIN
22T1 PRKAG2-related cardiomyopathyCardiovascular6.918.56.183.518.251AOC 1072
23T1 Cholestatic hepatitis6.888.57.527.232AX-0810 x AX-1412
24T1Precursor B-lymphoblastic leukemia acuteOncology6.8878.332105.716HY004
25T1Zika virus infectious diseaseInfectious Disease6.8784.048.315.517TELRATOLIMOD
26T1brainstem cancerOncology6.8775.386.22105.951CATEQUENTINIB
27T1 Prostate Carcinoma Metastatic in the BoneOncology6.8665.63106.271ENZALUTAMIDE
28T1Locally Recurrent Breast CarcinomaOncology6.8697.6724.8210PACLITAXEL
29T1 Abnormal uterine bleeding due to uterine fibroWomen's & Reproductive Health6.8596.6727.672SHR7280
30T1 hereditary cancerOncology6.8492.357.358.251GeneMate®
31T1thrombocytopaeniaHematology6.8497.525.519ELTROMBOPAG
32T1 Retinal DystrophyOphthalmology6.876.46.146.513AAV-CNGB3 x AAV-CNGA3 x AAV-UPF1 x AAV-RPGR x AAV-RPE65 x AAV-AIPL1 x AAV-RDH12 x AAV-GAD x AAV-hAQP1
33T1 Autoimmune deficiency syndromeImmunology & Inflammation6.876.426.526.681RF-GS04
34T1NK-cell lymphomaOncology6.897.225.837Brentuximab Vedotin x CYCLOPHOSPHAMIDE x PREDNISONE x DOXORUBICIN x VINCRISTINE
35T1 Menopause related conditionsWomen's & Reproductive Health6.7996.6726.823PROGESTERONE
36T1 Intestinal DisorderGastroenterology6.7856.548.938.251Compound Glutamin Enterosoluble Capsule
37T1 T-cell depletion6.7787.528.251ABO-2015
38T1 Acute myocardial infarction of anterior wallCardiovascular6.7492.926.18.251ABCIXIMAB
39T1 Acute leukemiasOncology6.738.56.6728.251ALA-101
40T1 Chronic pain following amputation6.738.56.6728.251CA-051
41T1 Early-onset obesityMetabolic & Endocrine6.738.56.6728.251MeiraGTx-BDNF
42T1 Neuropsychiatric symptomsNeurology/CNS6.738.56.6728.251SUVN-L3307032
43T1 Other inflammatory disorders of penisImmunology & Inflammation6.738.56.6728.251SAN903
44T1 Other inflammatory liver diseasesImmunology & Inflammation6.738.56.6728.251TP-317
45T1 Pre-B Acute Lymphoblastic LeukemiaOncology6.738.56.6728.251CD22-CAR-HSC
46T1 Zoster ocular diseaseOphthalmology6.738.56.6728.251ADAM15 AbIMP
47T1 Carcinoid tumor of the small bowelOncology6.7294.794.396.54PALTUSOTINE
48T1MISCELLANEOUS TUMORSOncology6.728825.754GF-CART01
49T1gynecologic cancerOncology6.6876.558.8554.071Avutometinib x defactinib
50T1 erythrocyte disorderHematology6.6876.185.597.672MITAPIVAT
51T1 Ocular inflammationImmunology & Inflammation6.658.54.135.646.513IVIEW-1701
52T1 Batten Disease6.658.56.6727.232RGX-181
53T1NUT CarcinomaOncology6.6465.428.75101.744ZEN-3694
54T1 Epidermal nevi6.64765.268.251NEDOMETINIB
55T1B Acute Lymphoblastic Leukemia, Not Otherwise Oncology6.6196.6724.599Anti-CD22 CAR-expressing T Lymphocytes x CYCLOPHOSPHAMIDE x FLUDARABINE
56T1 Other disorders of amino-acid metabolismMetabolic & Endocrine6.618.56.527.232Di-substituted pyrazole compounds
57T1Epithelial tumorsOncology6.5974.016.79105.471NG-641
58T1 myocardium diseaseCardiovascular6.5957.17.657.671MYOTECT
59T1 aggressive cancerOncology6.598.52.427.357.232KB-001
60T1 Benign Recurrent Intrahepatic Cholestasis6.5793.854.96.54LINERIXIBAT x URSODIOL
61T1 Complication of intravascular line6.5695.3328.251SIROLIMUS
62T1 Irregular sleep wake rhythm disorder6.5695.3328.251LEMBOREXANT
63T1Hematological neoplasmOncology6.554.58.138.52100.863VVD-130850 x PEMBROLIZUMAB
64T1 Antibody-mediated rejectionNephrology/Urology6.5486.6728.251CID-103
65T1 Primary Myelofibrosis with CALR MutationOncology6.5486.6728.251INCA033989
66T1 chemotherapy-induced neuropathyNeurology/CNS6.5486.6728.251CNTX 6016
67T1 Stress disorders6.5373.817.638.251SPC-15
68T1 Hantavirus Infections6.5374.586.588.251FX06
69T1Hashimoto DiseaseImmunology & Inflammation6.5265.98.585.371LINSITINIB
70T1Systemic Inflammatory Response SyndromeImmunology & Inflammation6.564.927.24104.951RILDINADSTROCEL
71T1 Venezuelan equine encephalitis virus infectionNeurology/CNS6.592.785.128.251V4020
72T1 Subcutaneous TissueOncology6.4974.965.98.251ANK-101 x CEMIPLIMAB
73T1 muscular dystrophy-dystroglycanopathyMusculoskeletal6.498.54.63.68.251MLAB-002
74T1 Polyneuropathy due to diabetes mellitusMetabolic & Endocrine6.4895.3327.672CEBRANOPADOL
75T1 Parkinson's disease with dyskinesiaNeurology/CNS6.468.53.444.468.251CSTI-200
76T1Fuchs' endothelial dystrophyOphthalmology6.4575.176.295.954SCO-116
77T1 Capillary Malformation-Arteriovenous MalformatCardiovascular6.458.54.423.618.251GPX-Clear Embolic Device
78T1 Resistant hypertensive disorderCardiovascular6.4465.337.687.261SZ005
79T1 Adenovirus InfectionInfectious Disease6.4393.064.398.251Adenovirus Vaccine
80T1hematopoietic/lymphoid cancerOncology6.4378.7524.478ABO-2015
81T1Prematurity of infantOphthalmology6.4265.538.413.395IBUPROFEN
82T1 hypertension in pregnancyCardiovascular6.4256.397.767.671Gravidol
83T1 monogenic diseaseMetabolic & Endocrine6.4276.114.676.821FBX-201
84T1 Chronic inflammatory disorders of orbitImmunology & Inflammation6.4286.527.672FT751
85T1 Chronic nonalcoholic liver diseaseGastroenterology6.378.55.3328.25117-β-HSD-13 inhibitor
86T1 Hand-Foot SyndromeRare/Genetic6.3664.897.97.261Proprietary Lead Compound
87T1Metastatic Prostatic AdenocarcinomaNephrology/Urology6.3575.835.855.133Abscopal 1001
88T1 Takotsubo syndromeCardiovascular6.3474.798.076.271GRK5 Inhibitor
89T1 EncephalopathiesNeurology/CNS6.3466.395.796.513BL-001
90T1Bone cancerOncology6.334.56.88.975.811Denosumab Biosimilar
91T1Benign neoplasm of prostateOncology6.3265.927.125.358DUTASTERIDE
92T1 Malignant Thoracic NeoplasmOncology6.3186.36.4308.251ENRISTOMIG
93T1 Aortic aneurysms and dissectionsCardiovascular6.2892.64.318.251ULINASTATIN x THYMALFASIN
94T1 Fibrinogen deficiencyHematology6.2774.335.688.251FIBRINOGEN, HUMAN
95T1Lung DiseasesImmunology & Inflammation6.2556.129.262.893UPAMOSTAT
96T1 Chronic HIV infectionImmunology & Inflammation6.2575.214.317.261LERONLIMAB
97T1Severe asthmaCardiovascular6.2564.617.52104.951DEPEMOKIMAB
98T1 Septal defectCardiovascular6.2454.518.238.251Ultrasept Cribriform Device
99T1Obstructive cardiomyopathyCardiovascular6.2447.789.14.371DEXPROPRANOLOL
100T1pulmonary heart diseaseCardiovascular6.2356.139.63.592NOGMT-based Products
101T1SteatohepatitisMetabolic & Endocrine6.2365.859.382.181SNA-003
102T1 Bone hyperplasiaMusculoskeletal6.2293.138.58.251Tiao Gu Pian
103T1Dyskinesia6.2275.915.7354.598AMANTADINE HYDROCHLORIDE
104T1 Adult Pure Erythroid LeukemiaOncology6.2191.385.598.251CYTARABINE x CLOFARABINE x FILGRASTIM x DILANUBICEL
105T1Giant Cell TumorsOncology6.274.796.455.691HY035
106T1 Fibrotic lymphadenopathy6.28.5526.922OPK-88006
107T1 Myoclonic disorder6.198.53.962.958.251RC-001
108T1 Eosinophilic Endomyocardial DiseaseCardiovascular6.1785.3328.251YH35324
109T1 Malignant neoplasm of cardio-esophageal junctiOncology6.1785.3328.251JZP898
110T1Pulmonary hypertension due to interstitial lunCardiovascular6.1655.79.263.641RT234-ILD PH
111T1 Anemia of chronic inflammationImmunology & Inflammation6.1676.6728.251DISC-0974
112T1 Aspirin-exacerbated respiratory diseaseRespiratory6.1676.6728.251IFETROBAN
113T1 Behçet's disease6.1676.6728.251PENTOXIFYLLINE
114T1 Hypoglycemia, leucine-inducedMetabolic & Endocrine6.1676.6728.251Baqsimi
115T1 PF-ILD-progressive fibrosing interstitial lungInfectious Disease6.1676.6728.251PARIDIPRUBART
116T1 question whether diagnosed with Crohn’s diseasImmunology & Inflammation6.1676.6728.251AGMB-129
117T1 Inflammatory disorder of the respiratory tractImmunology & Inflammation6.128.55.9208.251TRPV4 antagonist
118T1Chronic MigraineNeurology/CNS6.1265.327.225.691ALMA Lens
119T1Metastatic LiposarcomaOncology6.114.56.088.24103.761BTX-A51
120T1diabetic macular edemaCardiovascular6.1136.599.63103.181EOM147
121T1 B-cell neoplasm6.155.536.968.251SG299
122T1heart valve diseaseCardiovascular6.155.458.865.572TaurusWave
123T1childhood cancerOncology6.1568.642.9717NY-303
124T1Acute bronchiolitis caused by respiratory syncInfectious Disease6.0964.818.534.471V-306
125T1Pulmonary Heart DiseaseCardiovascular6.0855.599.64.031CardiALLO
126T1 Bone metabolism disordersMetabolic & Endocrine6.0856.456.316.823Osteoprotegerin ELISA
127T1 fetal and neonatal alloimmune thrombocytopeniaHematology6.0773.624.698.251RLYB212
128T1Stimulant use disorder6.0766.446.762.735SBS-518
129T1 Meningitis caused by echovirusInfectious Disease6.068.52.54.288.251OG716
130T1regional pain syndromeRare/Genetic6.0564.597.794.332HZT-501
131T1 Chronic motor tic disorder6.0565.425.77.261ELCUBRAGISTAT
132T1Chronic coronary syndromeCardiovascular6.0364.58.723.674PRASUGREL HYDROCHLORIDE
133T1Proliferative retinopathy due to diabetes mellMetabolic & Endocrine6.0264.788.124.631BI 764524
134T1myeloid neoplasmOncology6.0165.38.083.142FCN-338
135T1metabolic dysfunction-associated steatohepatitMetabolic & Endocrine6.0165.039.382.181LOY-002
136T1 Steroid-resistant nephrotic syndromeImmunology & Inflammation6.0174.145.726.681IDX9054
137T1 Malignant neoplasm in full remissionOncology6.0193.3328.251TRX103
138T1 Other disorders of brainImmunology & Inflammation6.0193.3328.251PEArlboost
139T1 Tracheostomy infectionInfectious Disease6.0193.3328.251Antimicrobial Tracheostomy Tube
140T1 Inflammatory liposarcomaImmunology & Inflammation6.063.757.677.261IRX-4204
141T1 Delayed sleep-phase syndromePsychiatry6.067.528.251TASIMELTEON
142T1 Response Evaluation Criteria in Solid TumorsOncology5.9976.67258.251B7-H3 CAR T cells; SJCARB7H3_41BBL infusion
143T1 ampullary cancerOncology5.9876.6726.54ONVANSERTIB
144T1 EndophthalmitisInfectious Disease5.9771.818.466.941iFAST AST Platform
145T1Radiation-induced mucositis5.9758.3328.754.3110GM-1111
146T1Epithelial neoplasmOncology5.9663.796.65105.031NG-641
147T1B-Cell LeukemiaOncology5.9675.356.5810316CC312
148T1Inflammatory Bowel DiseasesGastroenterology5.9647102.591Ezrin peptides
149T1Chronic inflammatory disorderImmunology & Inflammation5.9555.427.534.951BARICITINIB
150T1 respiratory tract injuryRespiratory5.9554.587.496.681Recombinant Hemopexin
151T1 Chronic ulcer of foot5.9582.95.118.251AMINOLEVULINIC ACID
152T1Advanced retinal diseaseNeurology/CNS5.9563.328.973.9610CG-EY1
153T1Fibrotic lung diseaseRespiratory5.9454.739.263.641ME-015
154T1Lung diseaseInfectious Disease5.9454.739.263.641BV500
155T1 Sexual desire disorderPsychiatry5.94556.928.251Libicare
156T1Primary fibromyalgia syndromeImmunology & Inflammation5.9466.7129.582.8418TELITACICEPT
157T1Type 1 Diabetes Mellitus with Hypoglycemia witMetabolic & Endocrine5.9476.6725.935ZT-01
158T1 thromboembolic disease5.9255.347.566.021SKB336
159T1 Device related infectionInfectious Disease5.928.52.952.988.251CYCLOSPORINE
160T1 Precancerous lesionsInfectious Disease5.928.5427.232PVX-8
161T1 Acquired angioedemaImmunology & Inflammation5.9164.035.8107.811DEUCRICTIBANT
162T1Immune System DiseasesImmunology & Inflammation5.9156.446.155.831MDI-0355 x MOD-C x MOD-D x ALVX-A
163T1Macular dystrophyOphthalmology5.914.54.269.39102.252AMTX-100 CF3
164T1Acute allergic reactionImmunology & Inflammation5.9155.768.623.522IsiCort
165T1 Lipid Disorders5.98.55.4307.232Fatostatin
166T1 Parainfluenza Virus InfectionInfectious Disease5.9556.728.251ELRE081 Influenza virus
167T1Systemic candidaInfectious Disease5.954.988.875.031FLUCONAZOLE
168T1Congenital immunodeficiency diseaseImmunology & Inflammation5.894.55.599.64.031Thymopolypeptides for Injection
169T1congenital metabolic diseaseCardiovascular5.894.55.599.64.031PAROMOMYCIN SULFATE
170T1 Vascular skin abnormalityDermatology5.8953.758.318.251SIROLIMUS
171T2Fatigue Syndrome, ChronicNeurology/CNS5.8964.58.7253.982NORKETOTIFEN
172T2Inflammatory joint diseaseOncology5.873.57.34102.152PrTrispan
173T2Atherosclerosis obliteransInfectious Disease5.8764.587.894.281CLBS12
174T2Metastatic malignant neoplasm to soft tissuesOncology5.8793.3327.263ANK-101 x CEMIPLIMAB
175T2Rare disease5.8777.4522.0825MDI-0355 x MOD-C x MOD-D x ALVX-A
176T2Malignant neoplasmsOncology5.854.56.48.640.6851JS201
177T2Tick-Borne DiseasesInfectious Disease5.8553.927.918.251pGOLD multiplexed assay kits
178T2Secondary narcolepsyNeurology/CNS5.8535.777.95105.111SERDEXMETHYLPHENIDATE
179T2Glioblastoma5.8445.7210100.471BDTX-1535 x BDTX-4933
180T2Radiation fibrosis - lungNeurology/CNS5.844.55.639.723.451ALT-100
181T2MALIGNANCIESOncology5.8476.6724.319CN1
182T2Melanoma In SituOncology5.8364.176.257.261Sofusa® DoseConnect™
183T2Bacteremia caused by Methicillin resistant Sta5.8393.3326.54EXEBACASE
184T2Campylobacter Infections5.828.53.3328.251Campylobacter Vaccine
185T2Infectious bursal disease5.828.53.3328.251Poultry Vaccine
186T2Neutrophilic disorderDermatology5.828.53.3328.251KP301
187T2OL(1)p53Oncology5.828.53.3328.251CL04177 x CL04183
188T2MicroangiopathyCardiovascular5.8155.078.095.371CALCIUM DOBESILATE
189T2H1N1 Flu (Swine Flu)5.8162.628.237.261RNAi-based Treatment for Swine Flu
190T2B and T cell defects5.855.314.598.251Thymopeptide Enteric-coated Capsules
191T2T-cell deficiency5.855.314.598.251Thymopeptide Enteric-coated Tablets
192T2Brain Injury5.7954.929.763.061PolarCap® System
193T2Pain lumbosacralMusculoskeletal5.79556.547.671Bals Sulphur Gel
194T2disc prolapse5.7863.288.15.951Cytotron
195T2ThromboangiitisCardiovascular5.774.54.797.096.681ARGATROBAN
196T2Chronic inflammatory demyelinating polyradiculImmunology & Inflammation5.7754.637.532.8412Flusalazine
197T2Typical Teratoid Rhabdoid TumorOncology5.7766.196.213.592Otviciclib
198T2Psoriasis-related juvenile idiopathic arthritiImmunology & Inflammation5.7766.044.595.572ADALIMUMAB
199T2Chronic pain following repair of hernia5.7766.6728.251ROPIVACAINE
200T2EGFR Exon 20 Insertion Mutation5.7766.6729.011FIRMONERTINIB
201T2Free-living amoeba infectionInfectious Disease5.7766.6728.251NITROXOLINE
202T2Genetic obesity disorderMetabolic & Endocrine5.7766.6728.251SETMELANOTIDE
203T2High Grade B-Cell Lymphoma with MYC and BCL2 ROncology5.7766.6728.251GOLCADOMIDE
204T2Lower extremities ulcers ofCardiovascular5.7766.6728.251PUDK-HGF
205T2Residual DiseaseOncology5.7766.6728.251DATOPOTAMAB DERUXTECAN
206T2mitochondrial disease/disorder5.7766.6728.251SONLICROMANOL
207T2SYNGAP1-related developmental and epileptic enNeurology/CNS5.768.56.6728.251PRAX-090
208T2MELAS SyndromePsychiatry5.754.55.729.92.341SONLICROMANOL
209T2Diffuse GliomaOncology5.7565.576.872.951SAFUSIDENIB
210T2Mixed Phenotype Acute LeukemiaOncology5.7566.175.622.929ZIFTOMENIB
211T2Mood DisordersPsychiatry5.755828.251PIRACETAM
212T2Granulomatous polyangiitisCardiovascular5.734.55.028.144.283FLUDARABINE x CYCLOPHOSPHAMIDE
213T2Pancreatic Undifferentiated CarcinomaOncology5.7354.38103.311AVOTACICLIB
214T2Congestion5.7353.727.598.251Lymphomyosot
215T2Major depressive disorder, recurrent episodePsychiatry5.7366.528.251SEP-4199
216T2Eye disordersImmunology & Inflammation5.7263.855.58.251PEArlboost
217T2SKIN DISORDERSImmunology & Inflammation5.7263.855.58.251PEArlboost
218T2Arthritis, JuvenileImmunology & Inflammation5.7255.965.895.274SARILUMAB
219T2hidradenitis suppurativaInfectious Disease5.756.27.6131BGB-45035
220T2Metastatic Breast Carcinoma in the SkinOncology5.69657.53.761REM-001
221T2Hepatic cancerOncology5.6946.05102.491VEBRELTINIB
222T2Erectile dysfunction due to endocrine diseaseOphthalmology5.6966.6727.232GW-870086
223T2Urinary SystemInfectious Disease5.6836.358.466.52Lysine Acetylsalicylate for Injection 0.25g
224T2Thyroid nodulesMetabolic & Endocrine5.6852.828.548.251mir-THYpe
225T2Pulmonary congestion5.6853.537.598.251GUAIFENESIN
226T2Associated with other malignanciesOncology5.688.53.3326.513TABELECLEUCEL
227T2Pain disorders5.6762.927.793.892THC knockout Program
228T2aortic diseaseCardiovascular5.6654.349.054.281Thoraflex™ Hybrid device
229T2Primary Immunodeficiency DiseasesImmunology & Inflammation5.6554.827.434.931OpCT-001
230T2Acute suppurative otitis media5.6591.253.427.672TELITHROMYCIN
231T2ADHD, predominantly inattentive type5.659228.251Metadoxine
232T2Acute headache due to craniotomy5.659228.251BUPIVACAINE HYDROCHLORIDE x DEXMEDETOMIDINE
233T2Amanita poisoning5.659228.251Silybin
234T2Anastomotic infectionInfectious Disease5.659228.251VORICONAZOLE
235T2Aspirin exacerbated respiratory diseaseRespiratory5.659228.251IFETROBAN
236T2Back muscle spasms5.659228.251TOLPERISONE
237T2Bacterial enteritis of intestineInfectious Disease5.659228.251OPS-2071
238T2Bacterial infection due to streptococcus, grouInfectious Disease5.659228.251GBS Vaccine
239T2Bipolar I disorder, most recent episode manicPsychiatry5.659228.251KarXT x Lithium cation x Valproate x LAMOTRIGINE
240T2Bipolar disorder, most recent episode depressiPsychiatry5.659228.251ALTO-100
241T2Chronic kidney disease due to type 1 diabetes Metabolic & Endocrine5.659228.251BARDOXOLONE METHYL
242T2Chronic pain due to malignant neoplastic diseaOncology5.659228.251QIXLEEF
243T2Chronic radiation ulcer5.659228.251Fibrin Sealant (Tisseel)
244T2Clear cell adenocarcinoma of peritoneumOncology5.659228.251LORIGERLIMAB
245T2Cushing disease due to increased ACTH secretioOncology5.659228.251CLOFUTRIBEN
246T2Depressive disorder in remissionPsychiatry5.659228.251PLOSARACETAM
247T2Destruction5.659228.251RF-based Body Contouring & Fat Destruction Platform
248T2Dyskinetic syndromeRare/Genetic5.659228.251VALBENAZINE TOSYLATE
249T2Edematous skinDermatology5.659228.251COLLAGENASE CLOSTRIDIUM HISTOLYTICUM
250T2Endometriosis externaWomen's & Reproductive Health5.659228.251LINIFANIB x AFATINIB x AXITINIB
251T2Extravasation injury5.659228.251Vedette®
252T2FIGO Grade 1 Endometrial Endometrioid AdenocarOncology5.659228.251TIRZEPATIDE
253T2Fracture of metatarsal boneMusculoskeletal5.659228.251Photodynamic Bone Stabilization System
254T2Fracture of phalanx of foot5.659228.251Photodynamic Bone Stabilization System
255T2Gingival disease due to dental plaque5.659228.251CETYLPYRIDINIUM CHLORIDE x Zinc cation x Dentalfluoro
256T2Hemophilic arthropathyHematology5.659228.251PTI-101
257T2Herpes simplex type 2 infectionInfectious Disease5.659228.251VALACYCLOVIR
258T2Immune effector cell-associated HLH-like syndrRare/Genetic5.659228.251RUXOLITINIB
259T2Infection by SchistosomaInfectious Disease5.659228.251PRAZIQUANTEL, (R)-
260T2Landouzy-Dejerine syndromeRare/Genetic5.659228.251AOC-1020
261T2Long-chain 3-hydroxy-acyl-CoA dehydrogenase de5.659228.251TRIHEPTANOIN
262T2Loss of teeth due to trauma, extraction, or pe5.659228.251Adipearl
263T2Lymphoma, Non-HodgkinOncology5.659228.251FE 203799
264T2Memory defects5.659228.251Aralia ginseng root x GINKGO
265T2Mixed venous and arterial5.659228.251ADRC technology
266T2Mucor infectionInfectious Disease5.659228.251YiGanKang Injection
267T2Myelodysplastic/Myeloproliferative Neoplasm wiOncology5.659228.251ROPEGINTERFERON ALFA-2B
268T2Pain due to neoplastic diseaseOncology5.659228.251METHADONE HYDROCHLORIDE
269T2Pancreatic DiseasesGastroenterology5.659228.251BAB-803
270T2Peripheral angiopathy due to diabetes mellitusMetabolic & Endocrine5.659228.251ASPIRIN
271T2Post-COVID syndromeInfectious Disease5.659228.251Convalescent Serum Therapy
272T2Postoperative infection (disorder)Infectious Disease5.659228.251CEFAZOLIN
273T2Primary haemophagocytic lymphohistiocytosis5.659228.251EMAPALUMAB
274T2Pseudomonal infectionsInfectious Disease5.659228.251AZITHROMYCIN
275T2Reduced ejection fraction co-occurrent and dueCardiovascular5.659228.251APD418
276T2SCN8A-related epilepsy with encephalopathyNeurology/CNS5.659228.251RELUTRIGINE
277T2Scoliosis, early-onset, severeMusculoskeletal5.659228.251Magnetically Growing Rod
278T2Septic coagulopathy5.659228.251THROMBOMODULIN ALFA
279T2Small cell carcinoma of the ovary, hypercalcemOncology5.659228.251TAZEMETOSTAT
280T2Statin-induced myopathyMusculoskeletal5.659228.251ROSUVASTATIN
281T2Tear disorder5.659228.251Systane Lubricant
282T2Trochanteric syndromeRare/Genetic5.659229.011AUTOLOGOUS PLATELET RICH PLASMA
283T2Urgency-frequency syndromeNephrology/Urology5.659228.251Oxybutynin x Oxybutynin x Oxybutynin x Oxybutynin x Solifenacin x Tolterodine x Tolterodine x Trospium x Darifenacin x Fesoterodine
284T2Varicose veins of lower extremity5.659229.011CALCIUM DOBESILATE
285T2White spot lesions of teeth5.659228.251OrthoClean
286T2Antibody deficiencyImmunology & Inflammation5.6456.47.246.681IVIG
287T2Skin lesionsDermatology5.6353.996.738.251RenuDermcell
288T2Metastatic Malignant NeoplasmOncology5.634.56.569.090310PEMBROLIZUMAB
289T2Invasive pneumococcal disease5.6383.3328.251RVX-001
290T2Other forms of heart disease5.6383.3328.251Kylo-0603
291T2reproductive organInfectious Disease5.6254.478.854.071AZITHROMYCIN
292T2Prosthesis-Related InfectionsInfectious Disease5.6282.572.988.251Non-contact Induction Heating Device
293T2Digestive System DiseasesGastroenterology5.6257.528.251Pancreatin Enteric-coated Tablets
294T2Genetic Diseases, Inborn5.628.53.6724.478LEOPARD
295T2Other peripheral vertigo5.625826.823Arlevert
296T2Primary apnea of premature newborns5.6257.528.251CAFFEINE CITRATE
297T2Primary apnoea of premature newborns5.6257.528.251CAFFEINE CITRATE
298T2Primary Open Angle GlaucomaOphthalmology5.61555.677.232BETAXOLOL
299T2Zika Virus InfectionInfectious Disease5.651.678.318.251Nobivac
300T2Acute pain due to injury5.64.55.19102.111Mericaine 4% Gel
301T2EnteropathyImmunology & Inflammation5.671.955.987.671EnteroTracker®
302T2Advanced Biliary Tract CarcinomaOncology5.5864.458.593.021ST-01156
303T2developmental and epileptic encephalopathy, 14Neurology/CNS5.588.53.861.25.935ABS-1230
304T2Generalized keratoacanthomaOncology5.5890.423.88.251DARLEUKIN x ONFEKAFUSP ALFA
305T2Chronic kidney disease due to type 2 diabetes Metabolic & Endocrine5.5863.332108.251rilparencel
306T2Acute GVH disease5.579227.232IVARMACITINIB
307T2Burns of multiple sites5.579227.232MTX-001
308T2EBV-Related LymphomaOncology5.579227.232TABELECLEUCEL
309T2Haemodialysis complication5.579227.672Crude heparin
310T2Intraepithelial neoplasia due to human papilloOncology5.579227.232Recombinant 15-valent Human Papillomavirus Vaccine
311T2Pruritus due to systemic disorderDermatology5.579227.672HSK21542
312T2Vitreoretinal traction syndromeRare/Genetic5.579227.672FIBRINOLYSIN, HUMAN
313T2Muscular painInfectious Disease5.564.51.257.766.461Flarin
314T2Arthritis of kneeImmunology & Inflammation5.5655.079.051.674SOMATROPIN x AUTOLOGOUS PLATELET RICH PLASMA
315T2Neuropsychiatric disordersRare/Genetic5.568.54.5505.954SPT-348
316T2Locally Advanced Urothelial CarcinomaOncology5.5658.3325.624.748PADCEV x KEYTRUDA
317T2Cerebral Amyloid Angiopathy, APP-RelatedCardiovascular5.558.53.8408.251ALZ-1903
318T2Carcinoma, Non-Small-Cell LungOncology5.5556.528.484.527AMIVANTAMAB
319T2anaplastic lymphoma kinaseOncology5.544.56.338.021.748CERITINIB
320T2Manic state5.5457.527.232Haloperidol Injection
321T2Liver CancerOncology5.5245.43102.491ENB-871
322T2Autonomic failure syndromeNeurology/CNS5.5263.157.015.951DROXIDOPA
323T2Acute Lymphoblastic LeukemiaOncology5.5116.569.911007NEBRATAMIG
324T2Huntington's DiseaseNeurology/CNS5.51269.737.22079BEVANTOLOL HYDROCHLORIDE
325T2Mycobacterial disease5.5173.764.435.463RIFABUTIN
326T2intellectual disability, autosomal dominant 5Neurology/CNS5.518.54.723.188.251STOKE ASO
327T2Immune system disorders5.514.55.696.156.271IMMODIN
328T2premenstrual syndromeCardiovascular5.5154.387.695.191PROGESTERONE
329T2Complication due to and following neuromusculaNeurology/CNS5.519227.263SUGAMMADEX x ROCURONIUM BROMIDE
330T2Parenteral nutrition-related hepatitisInfectious Disease5.519226.823Fish Oil/Glycerol/Egg Lecithin-based Emulsion
331T2Rosacea, erythematous telangiectatic typeOncology5.519226.513TETRASUL
332T2Malignant Peripheral Nerve Sheath TumorOncology5.563.947.673.961PAMIPARIB
333T2Epileptic encephalopathy with continuous spikeNeurology/CNS5.564.325.875.191APINOCALTAMIDE
334T2Autism Spectrum DisorderPsychiatry5.494.54.779.91.592GXV-001
335T2High grade serous carcinomaOncology5.4963.756.384.713RUCAPARIB CAMSYLATE x NIVOLUMAB
336T2Degenerative disorder of muscle5.4883.850.68.251SIR4156
337T2humoral hypercalcemia of malignancyOncology5.4857.526.513DENOSUMAB
338T2Vitreoretinal Disorder5.4790.937.048.251Resolv ER™
339T2Papillomavirus InfectionsOncology5.4793.483.658.251Therapeutic vaccine (cancer, virus) adjuvanted by interleukin-2
340T2Severe Acute Respiratory SyndromeInfectious Disease5.4653.8810103.611Zofin
341T2Testicular tumourOncology5.464.54.247.716.461ETOPOSIDE PHOSPHATE
342T2Chemotherapy-Induced ThrombocytopeniaHematology5.46562102.3123ROMIPLOSTIM
343T2Chronic lymphoid leukemia in relapseOncology5.469226.54Autologous Anti-CD20CAR-CD28-4-1BB-CD3zeta T-lymphocytes MB-106
344T2Hyperglycemia due to diabetes mellitusMetabolic & Endocrine5.469226.54GLOBALAGLIATIN HYDROCHLORIDE
345T2Acute Thymic Involution5.458.5228.251TBC190
346T2Cesium radioisotope5.458.5228.251NU02 Cesium decorporation
347T2Disease [Disease/Finding]Neurology/CNS5.458.5228.251Nanoligomer
348T2Endocrine, nutritional and metabolic diseasesMetabolic & Endocrine5.458.5228.251DBL003
349T2Fixation device5.458.5228.251Remote-Controlled Stem Cell Therapy
350T2Glucose transporter type 1 deficiency syndromeMetabolic & Endocrine5.458.5228.251CBT401
351T2Induced psychosisPsychiatry5.458.5228.251CSX-5000
352T2Insulin-dependent diabetesMetabolic & Endocrine5.458.5228.251Encapsulated live cells producing insulin
353T2MRSA sinusitisInfectious Disease5.458.5228.251OG716
354T2Multiple stab wounds5.458.5228.251DEEPCURE
355T2Non-invasiveOncology5.458.5228.251Biodegradable Nanoparticles
356T2Post-traumatic wound infection5.458.5228.251OTX PP02
357T2Rare genetic disease5.458.5228.251PASylated enzyme
358T2fracture non-union5.458.5228.251BiG-001 OIF/β-TCP
359T2histidyl-tRNA synthetase 1Rare/Genetic5.458.5228.251AT_1313
360T2laminitis5.458.5228.251FIDAXOMICIN
361T2virus related neoplasm/cancerOncology5.458.5228.251IM-02
362T2Acute and chronic respiratory failureRespiratory5.444.53.88103.611Ambroxol Hydrochloride
363T2Inflammatory conditions of jawImmunology & Inflammation5.4458.5722.8721DEXAMETHASONE SODIUM PHOSPHATE
364T2Post-traumatic painNeurology/CNS5.4458255.16Caffetin
365T2Infections of kidneyInfectious Disease5.4344.388.175.684FLOXACILLIN
366T2Partial tearMusculoskeletal5.4354.086.047.671Trace Orthopedics Tendon Fastener
367T2Chronic radiation enteropathyGastroenterology5.4274.616.277.261SYN-020
368T2IL-18BP deficiencyRare/Genetic5.4165.3328.251TADEKINIG ALFA
369T2Gastric DisordersGastroenterology5.454.375.57.232Betacid
370T2Primary immune deficiency disorder5.49225.276HUMAN IMMUNOGLOBULIN G
371T2Aortoiliac occlusive diseaseCardiovascular5.3991.176.258.251GADODIAMIDE
372T2Calcific arteriolopathy due to uremia5.3971.175.987.232HEXASODIUM PHYTATE
373T2Acute Duodenal Ulcer with Hemorrhage5.3956.6728.251Lansoprazole injection
374T2Allergic diseasesImmunology & Inflammation5.3956.6728.251Diclofenac Sodium Eye Drops
375T2Allergic reaction to insect biteImmunology & Inflammation5.3956.6728.251AFLODERM® Ointment
376T2Anemia due to and following chemotherapyHematology5.3956.6728.251EPOETIN ALFA
377T2Backache, NOS5.3956.6728.251ACECLOFENAC
378T2Bite of insectDermatology5.3956.6728.251TACT CREAM
379T2Chronic gouty arthritisImmunology & Inflammation5.3956.6728.251FEBUXOSTAT
380T2Drug-induced neutropeniaHematology5.3956.6728.251FILGRASTIM
381T2Generalized functional disorder5.3956.6728.251TRIMEBUTINE
382T2Infection caused by Clostridium novyiInfectious Disease5.3956.6728.251Facid
383T2Infection caused by beta-hemolytic StreptococcInfectious Disease5.3956.6728.251Facid
384T2Inflammatory disorder of musculoskeletal systeImmunology & Inflammation5.3956.6728.251BENZYDAMINE
385T2Injury of external auditory canalImmunology & Inflammation5.3956.6728.251CIPROFLOXACIN
386T2Intestinal infectious disease caused by anaeroInfectious Disease5.3956.6728.251Zydotum
387T2Lower limb ischemia5.3956.6728.251Neovasculgen
388T2Neonatal aspiration syndromesRare/Genetic5.3956.6728.251Omeprazole Sodium for Injection
389T2Oral Cavity and Lip Precancerous ConditionOncology5.3956.6728.251Straticyte
390T2Post-surgery back pain5.3956.6728.251Flamar MX
391T2Recurrent manic episodesPsychiatry5.3956.6729.011Milsaperidone (Bysanti)
392T2Transfusion-transmitted infectious diseaseInfectious Disease5.3956.6728.251Transfusion-transmitted Virus (TTV) Real Time PCR Kit
393T2Renal injuryNephrology/Urology5.3853.71102.111Exonox Renal ELISA
394T2Bone lossMusculoskeletal5.3853.336.428.251DENOSUMAB
395T2Corneal endothelial disorderOphthalmology5.374.53.897.765.276ZH906
396T2Non-Proliferative Diabetic RetinopathyCardiovascular5.3763.127.154.252TTAX01
397T2Acute dermatitisDermatology5.3754.654.997.671Septomida MD Spray
398T2Allergic disorder of skinInfectious Disease5.3754.425.317.671Histamine Human Immunoglobulin
399T2Metastasis to boneOncology5.36458.44.581SHR-2017
400T2Periapical diseaseInfectious Disease5.3553.755.78.251Cresatin
401T2Recurrent Fallopian Tube High Grade Serous AdeOncology5.359226.18Anti-VEGF Monoclonal Antibody x BEVACIZUMAB x CARBOPLATIN x GEMCITABINE x Pegylated Liposomal Doxorubicin Hydrochloride
402T2Recurrent Ovarian High Grade Serous AdenocarciOncology5.359226.18Anti-VEGF Monoclonal Antibody x BEVACIZUMAB x CARBOPLATIN x GEMCITABINE x Pegylated Liposomal Doxorubicin Hydrochloride
403T2Recurrent Primary Peritoneal High Grade SerousOncology5.359226.18Anti-VEGF Monoclonal Antibody x BEVACIZUMAB x CARBOPLATIN x GEMCITABINE x Pegylated Liposomal Doxorubicin Hydrochloride
404T2Sanfilippo SyndromeMetabolic & Endocrine5.348.51.684.238.251ALL-027
405T2Arthritis, RheumatoidImmunology & Inflammation5.3492.174.618.251Djit PIP
406T2Respiratory infections, chronic recurrentInfectious Disease5.3492.6707.672RSP-1502
407T2Moderate risk ofCardiovascular5.3456.67258.251OLEZARSEN
408T2Neurogenic InflammationGastroenterology5.34903.168.251CoolStat
409T2hemolytic disease of the fetusHematology5.3456.527.811NIPOCALIMAB
410T2Idiopathic bronchiectasisInfectious Disease5.3353.564.567.232Cefaclor Sustained-release Capsules
411T2Ornithine transcarbamylase deficiencyNeurology/CNS5.3354.086.147.261GTP-506
412T2Skeletal defects5.3375.1508.251Autologous Multipotent Mesenchymal Stem Cells
413T2Atherosclerotic occlusive diseaseCardiovascular5.3291.176.257.672LERODALCIBEP
414T2Metastatic malignant neoplasm to liverOncology5.323.55.61101.16TLR7 Agonist RO7119929 x TOCILIZUMAB
415T2Restriction5.3253.19.24.072VibraCool
416T2SpasmsWomen's & Reproductive Health5.323.55.957.575.031DROTAVERINE
417T2Edematous fibrosclerotic panniculopathy5.3265.625.156.823COLLAGENASE CLOSTRIDIUM HISTOLYTICUM
418T2Lung diseases due to external agentsRespiratory5.328.5226.513LM007
419T2Amyloid light-chain amyloidosisOncology5.3143.929.963.484DARATUMUMAB
420T2Primary hypertensionCardiovascular5.3145.17.684.823DOXAZOSIN MESYLATE
421T2Cushing's syndromePsychiatry5.3135.718.565.371RELACORILANT
422T2Hesitation wounds5.3156.6727.232InnovaMatrix® PD
423T2Hyperphenylalaninemia, non-phenylketonuric5.3156.6727.232SAPROPTERIN DIHYDROCHLORIDE
424T2Malignant melanoma with BRAF V600E mutationOncology5.3156.6727.232ENCORAFENIB
425T2Other functional intestinal disordersGastroenterology5.3156.6727.232ACTAPULGITE
426T2Ligament Injury5.3359.113.361CRMA®
427T2Spinal Cord InjuryNeurology/CNS5.3359.113.361MyndMove
428T2Traumatic injury5.3359.113.361ABCcolla® Bone Graft
429T2Clear cell endometrial carcinomaOncology5.34.54.869.491.371ADU-1805
430T2Severe coagulase-negative Staphylococcus infecInfectious Disease5.352.447.188.251Cefazedone Sodium for Injection
431T2Exocrine pancreatic dysfunctionGastroenterology5.2944.227.856.461SECRETIN SYNTHETIC HUMAN
432T2Intervertebral Disc Displacement5.2953.4285.031ZLift
433T2Mild neurocognitive disorderNeurology/CNS5.2862.56.875.691Fish Oil/Glycerol/Egg Lecithin-based Emulsion
434T2Cervical syndromeRare/Genetic5.2854.176.665.471Bals Sulphur Gel
435T2Acute disease of musculoskeletal systemMusculoskeletal5.2755.953.066.513CYCLOBENZAPRINE HYDROCHLORIDE
436T2Dementia due to cobalamin deficiencyNeurology/CNS5.2744.518.075.371MECOBALAMIN
437T2Juvenile psoriatic arthritis with psoriasisImmunology & Inflammation5.2755.634.594.823ETANERCEPT
438T2hemolytic disease5.264.54.297.166.11total bilirubin assay kit
439T2Acute respiratory diseaseRespiratory5.264.53.21102.862SuiShotⓇ TR
440T2Fracture repairMusculoskeletal5.2662.296.676.271OsteoAdapt SP
441T2Coenzyme Q deficiency5.268228.251UBIDECARENONE
442T2Injury of soft tissue of face5.268228.251A3T01
443T2Peripheral Artery Disease5.2544.739.542.591MOTIV Bioresorbable Scaffold
444T2Psychoactive substance use disorder, NOSPsychiatry5.2556.6726.823NarcoStem
445T2Transthyretin-mediated amyloidosisCardiovascular5.2556.6726.513VUTRISIRAN
446T2Non-MalignantOncology5.246527.672UM171 Cell Therapy
447T2T-cell AND/OR NK-cell neoplasmOncology5.2473.3329.011GENOLIMZUMAB
448T2Amyloid polyneuropathy type IRare/Genetic5.2256.67256.823EPLONTERSEN
449T2Cystic disease of liverGastroenterology5.2155.174.865.951ALBENDAZOLE
450T2Vaginal NeoplasmsOncology5.2153.335.568.251SPORLAC PLUS
451T2benign vaginal mixed tumorOncology5.2153.335.568.251Povidone Iodine Vaginal Effervescent Tablets
452T2Chronic ischaemic heart diseaseCardiovascular5.2156.6725.754MT-102
453T2PurpuraImmunology & Inflammation5.253.047.475.951PlasmaGlob
454T2Post-traumatic neuralgiaNephrology/Urology5.24.557.383.092AP707
455T2Rheumatism5.254.464.048.251ACECLOFENAC
456T2Anogenital candidiasisOncology5.256.227.53.6718TSC-203-A0201
457T2Open injury5.194.53.71102.111Yunnan Baiyao Woundplast
458T2Necrotic tumor5.194.52.927.7857.261Flaminal Hydro
459T2Carcinoma of ureterOncology5.1862.57.224.695Docetaxel x Icrucumab
460T2gastroesophageal adenocarcinomaOncology5.1846.797.1151.362KEYTRUDA x LENVIMA
461T2Acquired fibrinogen deficiency5.184.54.126.965.811FIBRINOGEN, HUMAN
462T2Postoperative Pain5.186526.513ROPIVACAINE
463T2Secondary malignant neoplasm of lungOncology5.189224.1320PEMETREXED
464T2Amyloid angiopathyCardiovascular5.1763.667.927.261RESAMIRIGENE BILPARVOVEC
465T2Retinal Vascular DisorderCardiovascular5.171.57.049.214.442UBX2048
466T2Knee Injury5.1752.417.017.671gMSC®1
467T2EpilepsyNeurology/CNS5.1618.45102.241OneRF System
468T2Perianal fistula due to Crohn's diseaseImmunology & Inflammation5.1673.3327.232AVB-114
469T2Spinal cord diseaseNeurology/CNS5.1543.996.647.671BAROPAN
470T2Infectious disorder of kidneyInfectious Disease5.1552.57.66.461Cefoperazone for Injection
471T2Liver FibrosisInfectious Disease5.142.55.6391.485Fuzheng Huayu Capsule
472T2Corneal DiseasesOphthalmology5.1463.154.936.2713DBT corneas
473T2Macular neovascularizationCardiovascular5.1463.154.936.2724D-150
474T2fallopian tube cancerOncology5.134.56.446.680.653PAMIPARIB
475T2Primary malignant neoplasm of liverOncology5.1335.61102.12CHEMOSAT Hepatic Delivery System
476T2Vena CavaCardiovascular5.1352.086.848.251sinus-XL
477T2SluggishnessGastroenterology5.1252.727.166.463Eucarbon® nutrition
478T2Hearing Loss, Hidden5.1173.3326.273CIL001
479T2MET mutation-related tumorsOncology5.117424.449AB-001
480T2Low Grade GliomaOncology5.145.417.253.611BDTX-1535
481T2Primary Systemic AmyloidosisMetabolic & Endocrine5.094.52.259.963.723FCN-338
482T2Pain inflammation activatedImmunology & Inflammation5.0994.5308.251GSK1482160
483T2Prohormone Convertase 1 DeficiencyRare/Genetic5.0894.530.66.513SETMELANOTIDE
484T2upper digestive tract disorderGastroenterology5.0853.285.038.251EvoEndo® System
485T2Bone and joint infectionInfectious Disease5.0816.72105.111Cefazolin Sodium for Injection
486T2ApoplexyCardiovascular5.0852.086.68.251Yizhi Kangnao
487T2Calcific tendinitis5.0861.175.988.251Pulse IVL System
488T2Hepatic carcinoma malignant primary recurrentOncology5.088225.954Huaier Extract Granule
489T2Interstitial lung fibrosisRespiratory5.0734.692.231Bovhyaluronidase azoximer
490T2Fatigue due to and following ischemic cerebrovCardiovascular5.072.56.36101.551BP1.3656
491T2Mucocutaneous ulcerInfectious Disease5.0752.926.666.461INTERFERON ALFA
492T2Moderate manic bipolar I disorderPsychiatry5.0756.6724.959LUMATEPERONE
493T2Bacterial infection of skinInfectious Disease5.062.56.258.134.471Levofloxacin Bluefish
494T2Mitochondrial metabolism defectRare/Genetic5.0536.496.694.751ELAMIPRETIDE
495T2Bone InfectionsInfectious Disease5.0554.155.8452.7217CIPROFLOXACIN
496T2Chemotherapy induced neutropeniaHematology5.0557.3825.50.643PEGFILGRASTIM
497T2Recurrent non-tuberculous mycobacterial infectInfectious Disease5.0553.33297.232DELPAZOLID
498T2Adult T-Cell Leukemia/LymphomaOncology5.044.54.177.743.531VALEMETOSTAT
499T2Fontan-associated liver diseaseImmunology & Inflammation5.048.5228.251EVerGel
500T2Chronic Pseudomonas aeruginosa infectionInfectious Disease5.0381.6706.513OMN-51
501T2Cervical VertebraWomen's & Reproductive Health5.0354.094.96.022Thermal Therapy Plaster
502T2Renal neoplasmsOncology5.0374.0608.251ARCHEXIN
503T2blood group incompatibility5.0391.2508.251RA02A x RA02B
504T2Locally advanced breast cancerOncology5.024.53.869.492.121177Lu-BetaBart; BetaBart; RV-01
505T2Candidal infectionsInfectious Disease5.0255.3328.251FLUCONAZOLE
506T2Methicillin-Sensitive Staphylococcus aureus InInfectious Disease5.0272.528.251CTI-005
507T2Autosomal Recessive Hypophosphatemia RicketsMusculoskeletal5.0182.294.48.251INZ-701
508T2Head and neck cancerOncology5.0115.910100.491Enoblituzumab; MGA271
509T2Recurrent Malignant GliomaOncology5.013.55.718.6952.341MT027 cells suspension; MT027 CAR-T cells; MT027 UCAR-T
510T2Progressive volume loss5.013.54.327.35.713STYLAGE®
511T3Escherichia coli InfectionsInfectious Disease5.0142.898.115.933Cefalexin Tablets
512T3Staphylococcus infectionInfectious Disease5.04.52.97.854.585Acetylspiramycin Tablets
513T3Spinal tumorsOncology4.9952.55.628.251BlackArmor® Carbon/PEEK Anterior Cervical Plate
514T3Chronic intestinal failureInfectious Disease4.9824.33103.291CR-13/01
515T3Marburg disease4.9881.675.746.513GALIDESIVIR
516T3Diarrhea post chemotherapyOncology4.9815.75101001CROFELEMER
517T3disease of the bloodInfectious Disease4.9817.249.524.031AMIKACIN
518T3Squamous Intraepithelial LesionsOncology4.9852.458.483.961Papilocare
519T3ACTH Syndrome, EctopicRare/Genetic4.9861.255.757.671OSILODROSTAT
520T3GLUT1 Deficiency Syndrome 1Metabolic & Endocrine4.9762.064.198.251TRIHEPTANOIN
521T3Acute respiratory infectionsInfectious Disease4.971.55.389.865.811NP-339
522T3fertility disorders4.9756.6723.4416FOLLITROPIN DELTA x Human Menopausal Gonadotropin
523T3Cholangiocarcinoma4.9435.469.182.111INFIGRATINIB
524T3Light chain diseaseOncology4.944.54.589.9604.032IPH6401 SAR514
525T3Bile DuctsInfectious Disease4.9453.117.164.331Cefazolin Sodium for Injection
526T3Retinal angiopathyCardiovascular4.9353.997.927.261Acid yellow 73 sodium salt
527T3Intestinal infections due to other organismsInfectious Disease4.935528.251Vabomere
528T3Systemic Juvenile Idiopathic ArthritisImmunology & Inflammation4.9215.678.573.561ANAKINRA
529T3complement 3 glomerulopathyNephrology/Urology4.924.54.026.256.674.597PEGCETACOPLAN
530T3shock syndromeRare/Genetic4.9235.838.512.351Dopamine Hydrochloride Injection
531T3IgE-mediated allergic disorderImmunology & Inflammation4.9252.755.317.671Kenota 1 Total IgE test system
532T3respiratory diseaseRespiratory4.9116.67103.523Madame Pearl's Cough Syrup
533T3End-stage renal diseaseNephrology/Urology4.94.52.679.972.111CSL525
534T3degenerative brain disease4.98.51.030.68.251Gene-cell therapy for Degenerative (brain) diseases
535T3Vasomotor rhinitisWomen's & Reproductive Health4.93.55.145.666.461ELINZANETANT
536T3HPV infectionOncology4.898.51.4308.251NTX-250
537T3Intrabony periodontal defectInfectious Disease4.887228.251MD05
538T3Neurotrophic keratoconjunctivitisNeurology/CNS4.887228.251NRO-1
539T3Non-small cell adenocarcinoma of lungRespiratory4.887228.2512,2'-DITHIODIETHANESULFONIC ACID
540T3Orolabial HSV infections4.887228.251HDIT101
541T3Paralysis due to lesion of spinal cordNeurology/CNS4.887228.251ExaStim
542T3Reduced ejection fraction co-occurrent and dueCardiovascular4.887228.251BC-007
543T3prostate cancer preventionOncology4.887228.251Theakine® Prost
544T3synaptopathyNeurology/CNS4.887228.251CIL001
545T3Malignant epithelial tumorOncology4.8755.585.330.245BCN077
546T3Salmonella infectionInfectious Disease4.874.51.628.176.241GSK4077164
547T3Epidermitis4.8663.3328.251NJ-09-EE
548T3Osteomyelitis caused by Staphylococcus aureusMetabolic & Endocrine4.8663.3328.251BX211
549T3Chylomicronemia syndromeMetabolic & Endocrine4.8554.215.576.684PRADIGASTAT x FENOFIBRATE x PRADIGASTAT x Fish Oil Capsules
550T3Hereditary angioedema with C1 esterase inhibitImmunology & Inflammation4.8573.284.038.251BMN-331
551T3Eye injuryOphthalmology4.853.54.418.852.771iNexin
552T3Cataracts, infantileOphthalmology4.8493.7507.672SVT-15473
553T3Condyloma acuminatum of the anogenital regionInfectious Disease4.8443.37.854.442Tsegardex
554T3pulmonary non-tuberculous mycobacterial infectRespiratory4.8362.194.436.461ARINA-1
555T3Endometrial cancerOncology4.8343.869.491.371DOSTARLIMAB
556T3Lumbar Vertebra4.8352.087.545.031Thermal Therapy Plaster
557T3Thoracic pain4.8352.087.545.031Biolevox Neuro
558T3Neuroendocrine TumorsOncology4.8216.329.081.6610VOROLANIB
559T3Fallopian tube cancerOncology4.8245.776.682.161BEVACIZUMAB
560T3Cryptococcal infectionsNeurology/CNS4.8243.337.525.271MAT2203
561T3Adrenal tumorsOncology4.8153.318.513.71TIGOZERTINIB
562T3Paralysis, Infantile4.853.982.728.251Aceglutamide for Injection
563T3ScarsPsychiatry4.87227.232Autologous Fibroblast Transplantation
564T3Advanced Hepatocellular CarcinomaOncology4.7916.36101.151CAR (hYP7)-T cells
565T3Hepatocellular CarcinomaOncology4.7916.36100.41IPILIMUMAB
566T3Chronic Lymphocytic LeukemiaOncology4.7916.549.4405EPOETIN ALFA
567T3Nystagmus, infantile4.7990.3808.251NERAMEXANE MESYLATE
568T3Pancreatic AdenocarcinomaGastroenterology4.794.51.777.855.837Anti-integrin Beta-6/MMAE Antibody-drug Conjugate SGN-B6A x PEMBROLIZUMAB x CISPLATIN x CARBOPLATIN
569T3Deep third degree burn injury4.7863.3327.672Recombinant Human Acidic Fibroblast Growth Factor For External Use
570T3feline leukemia virus infectionOncology4.7716.341002Speed Duo FeLV/FIV
571T3Urothelial CarcinomaOncology4.7716.368.6280145FUTIBATINIB
572T3Female genital tract infectionInfectious Disease4.7752.54.547.811CEFTAZIDIME
573T3Progressive WHO Grade 4 GliomaOncology4.7644.167.253.611TVI-Brain-1
574T3liver diseasesGastroenterology4.7644.55.814.353Dualase
575T3Allergic conditionsImmunology & Inflammation4.7652.175.317.671CHLORPHENOXAMINE
576T3ATTR AmyloidosisNeurology/CNS4.751.55.516.714.832Coramitug
577T3Transthyretin related familial amyloid cardiomCardiovascular4.751.55.516.714.833NTLA-2001
578T3transthyretin amyloidosisCardiovascular4.751.55.516.714.523INOTERSEN
579T3Radiation esophagitisOncology4.751.56.75101.261Avasopasem Manganese x GC4419
580T3Membranoproliferative GlomerulonephritisNephrology/Urology4.7552.64.77.671IPTACOPAN
581T3Metastatic malignant neoplasmOncology4.7426.019.81.13MASL
582T3Subcutaneous tumorOncology4.7451.985.118.251PetXmark
583T3Venous ulcer of leg4.7443.127.3955.031Venucreme
584T3respiratory tract diseaseRespiratory4.7316.269.860.8747Quadri-subtype Influenza VLP Vaccine
585T3Infection caused by anaerobic bacteriaInfectious Disease4.734.52.715.018.251GENTAMICIN SULFATE
586T3Advanced Head and Neck Squamous Cell CarcinomaOncology4.7135.259.460.571EMUNKITUG
587T3Bone loss in jawOncology4.7155.6808.251DENOSUMAB
588T3Diffuse midline glioma H3K27M mutationOncology4.7173057.232DORDAVIPRONE
589T3Head and Neck CarcinomaOncology4.6935.169.460.135IM-1021 x IM-3050 x IMM-ONC-01 x AL102 (varegacestat) x IM-1617 x IM-1335 x IM-1340
590T3Lip NeoplasmsOncology4.6953.034.55.935NIO® Laser Imaging System
591T3Diffuse midline glioma, point mutation K27M inOncology4.699008.251H3K27M Long Peptide Vaccine
592T3Immune dysfunction4.6816.39102.391ICLAPRIM
593T3Osteoblastic Metastatic Bone LesionOncology4.6852.174.528.251Samarium [153Sm] Lexidronam Injection
594T3Acute myeloid leukemiaOncology4.6716.049.440.383ETOPOSIDE PHOSPHATE
595T3Cytomegalovirus infectionInfectious Disease4.653.52.789.023.572LETERMOVIR
596T3thrombotic disease4.6517.118.265.41029ASPIRIN
597T3Optic Nerve DiseasesNeurology/CNS4.653.53.58.293.961NPX461
598T3Type II diabetesMetabolic & Endocrine4.6417.551005Sublingual Insulin
599T3periprosthetic joint infectionInfectious Disease4.645524.918PLG-0206
600T3Vaso-occlusive pain episode in sickle cell dis4.6324.039.241.514INCLACUMAB
601T3Coronary arteriosclerosisCardiovascular4.6316.95101.331SIMVASTATIN
602T3blood coagulation disorders4.6315.769.5251.9214Human Prothrombin Complex
603T3Resistant hypertensionCardiovascular4.6216.1101.962Aldosterone Synthase Inhibitor
604T3indolent lymphomaOncology4.6115.819.67010KPG-818
605T3CKDMetabolic & Endocrine4.6116.44102.941MW-401
606T3Obesity ManagementMetabolic & Endocrine4.6116.44102.941PEMVIDUTIDE
607T3Obesity-Related Malignant NeoplasmMetabolic & Endocrine4.6116.44102.191ABC-294640
608T3Ewing sarcoma / peripheral neuroectodermal tumOncology4.6170.425.354.471CIXUTUMUMAB
609T3chronic actinic dermatitisDermatology4.65228.251Fendactin
610T3Primary Peritoneal CancerOncology4.654.176.121.321AVB-001
611T3Breast CarcinomaOncology4.5915.87103.21PERTUZUMAB
612T3Strain - lesion4.5954256.513Venucreme
613T3Small cell lung cancer metastaticOncology4.5815.69.50.781SYS6043
614T3Ornithine transcarbamylase deficiencyMetabolic & Endocrine4.584.51.56.147.261SODIUM PHENYLBUTYRATE
615T3Nutritional supplement4.5855.2108.251Superchic
616T3Systemic infectionsInfectious Disease4.5741.258.176.681Cefazolin Sodium for Injection
617T3lung tumorOncology4.5616.75100.57Bronchoscope-guided Electrode
618T3Streptococcus infectionInfectious Disease4.5633.127.865.354Acetylspiramycin Tablets
619T3Cerebral vascular lesionCardiovascular4.5552.423.568.251Other TCM Patent Medicines
620T3Cancer anemiaOncology4.5316.29101.961AND017
621T3Chronic hyperglycaemiaMetabolic & Endocrine4.5217.11100.791TW68
622T3Pelvic Inflammatory DiseaseInfectious Disease4.5232.968.495.191Cefoxitin Sodium for Injection
623T3Pleura carcinomaOncology4.512.54.5101.181MT027
624T3Carcinoma squamousOncology4.511.55.15102.631IM-1021 x IM-3050 x IMM-ONC-01 x AL102 (varegacestat) x IM-1617 x IM-1335 x IM-1340
625T3Fungal infectionsInfectious Disease4.5115.619.863.331CASPOFUNGIN ACETATE
626T3Gram-Negative Bacterial InfectionsInfectious Disease4.511.55.817.455.191BAL2420
627T3Chronic Obstructive Pulmonary DiseaseGastroenterology4.516.68100.941Gamma glutamyl transferase assay kit
628T3Malignant epithelial neoplasmOncology4.4953.915.331.441121Pb
629T3Breast cancerOncology4.49171001ELINZANETANT
630T3Rheumatoid ArthritisImmunology & Inflammation4.4916.87100.462METHOTREXATE
631T3arthritis painImmunology & Inflammation4.4916.871003YJF-015
632T3Clark melanoma level 1Oncology4.496228.251BS-001
633T3Osteochondral injury4.496228.251Agili-C
634T3Paediatric acute-onset neuropsychiatric syndroNeurology/CNS4.496228.251NTI164
635T3Pain, PostoperativeImmunology & Inflammation4.496228.251TEV-'749
636T3Neurologic involvementCardiovascular4.4854.8308.251METHYLPREDNISOLONE
637T3Infection caused by Pseudomonas aeruginosaInfectious Disease4.4863.9607.261DXR inhibitor program
638T3Parenteral NutritionInfectious Disease4.4853.481.818.251NutriLock
639T35,10-Methylenetetrahydrofolate reductase4.4853.3328.251BETAINE
640T3Brain Injury, ChronicCardiovascular4.4853.3328.251CHOLINE ALFOSCERATE
641T3Caprine arthritis-encephalitisNeurology/CNS4.4853.3328.251Small Ruminant Lentivirus Antibody Test Kit, cELISA
642T3Chronic bronchial diseaseImmunology & Inflammation4.4853.3328.251Hedecid Syrup
643T3Correction4.4853.3328.251STYLAGE®
644T3Genitourinary tract infectionInfectious Disease4.4853.3328.251CELEX-250
645T3Infection by OesophagostomumInfectious Disease4.4853.3328.251ASHITAL 5% Injection
646T3Infection by StrongyloidesInfectious Disease4.4853.3328.251ASHITAL 5% Injection
647T3Infection in the elderlyInfectious Disease4.4853.3328.251Heartworm Antigen Test Kit
648T3MSI-H Colorectal CarcinomaOncology4.4853.3329.011PEMBROLIZUMAB
649T3Mood disorder with manic symptoms caused by hyGastroenterology4.4853.3328.251A Tai Ning
650T3ParasitosisPsychiatry4.4853.3328.251AQUACEN FORMALDEHYDE
651T3Primary herpes simplex infection of lipsInfectious Disease4.4853.3328.251Lipovir
652T3envenomation4.4853.3328.251Antitoxin for poison of European snake
653T3gallstone disease4.4853.3328.251Ursovef
654T3Urinary infectionInfectious Disease4.4715.76102.561NORFLOXACIN
655T3Negative symptoms in schizophreniaPsychiatry4.4516.53100.424HBL20030
656T3Biliary disordersGastroenterology4.4552.083.568.251Hydroxybutyloxide
657T3Vasomotor disturbance4.4542.795.666.461GS1-144
658T3Venous malformationsCardiovascular4.4463.8108.757.263QTORIN™ rapamycin
659T3Diffuse low grade B-cell lymphomaOncology4.4314.629.2950.33FS118
660T3neck syndromeRare/Genetic4.431.55.599.81.541LOXOPROFEN
661T3Deficiency anemiaHematology4.4315.91101.961Gastroretentive drug delivery formulation
662T3Cutaneous ulcersDermatology4.4351.673.988.251RGTA®
663T3chemotherapy-induced gastrointestinal mucositiGastroenterology4.43800.68.251MultiBiotic™
664T3Cystic Disease Of LungRespiratory4.4213.959.962.021ALBENDAZOLE
665T3Spasticity, severeNeurology/CNS4.4253.731.28.251Lioresal® Intrathecal
666T3Diabetes, type 1Metabolic & Endocrine4.411.55.48101.281DBLG1
667T3CarcinomaOncology4.415.48102.631Alertix TK1 ELISA
668T3Varicella Zoster InfectionInfectious Disease4.42.54.236.795.691FAMCICLOVIR
669T3Acute bronchitis with bronchospasmRespiratory4.453.3327.232Ambroxol Hydrochloride
670T3At increased risk for surgical blood lossOncology4.453.3327.232DENOSUMAB
671T3Pre-cancerous dysplasiaOncology4.453.3327.232VTP-200
672T3Via urogenital tractInfectious Disease4.453.3327.232OFLOXACIN
673T3neck-shoulder-arm syndromeRare/Genetic4.453.3327.672HP-3150
674T3Excessive Bleeding4.3954.5308.251AMINOCAPROIC ACID
675T3Radiation-Induced DermatitisOncology4.3816.591001LUT-014
676T3Melanoma-Pancreatic Cancer SyndromeOncology4.3716.54100.521Botensilimab / AGEN1181
677T3Metastatic Breast Carcinoma in the BrainOncology4.3616.511003Ferumoxytol x IRINOTECAN SUCROSOFATE
678T3Metastatic Breast Carcinoma in the LiverOncology4.3616.511002MELPHALAN x ERIBULIN x VINORELBINE x CAPECITABINE
679T3Enzootic diseaseInfectious Disease4.3651.673.638.251HYOGEN
680T3Rheumatoid arthritisNeurology/CNS4.3516.02101.921Atrosab
681T3Ovarian CarcinomaOncology4.3314.38100.161PACLITAXEL
682T3Malignant lung tumorsOncology4.3314.529.50.781EmboCept S DSM 50 μm
683T3Xerostomia caused by ionizing radiationOncology4.3324.529.81.541AAV-AQP1
684T3Bladder InfectionsInfectious Disease4.3354.340.66.513FLOXACILLIN
685T3Advanced Renal Cell CarcinomaOncology4.3214.199.811.621Sapanisertib (TAK-228; MLN0128; INK128)
686T3Diabetes, early-onsetMetabolic & Endocrine4.3124.41102.041IMCY-0098
687T3EstablishedMetabolic & Endocrine4.3124.41101.281TOL-3021
688T3large B-cell lymphomaOncology4.313.969.2950.611AXICABTAGENE CILOLEUCEL
689T3eye diseaseOphthalmology4.315.219.23.611ANGICYTE
690T3MelanomaOncology4.315.861050.11Tafinlar x Mekinist
691T3Dementia associated with Parkinson's DiseaseNeurology/CNS4.315.98100.91NBI-1117567
692T3Acute and chronic cholecystitis4.2953.3325.954AmnioWrap2
693T3Irritable Bowel SyndromeGastroenterology4.2815.639.312.451VIBEGRON
694T3Venous refluxGastroenterology4.2815.349.562.711VENCLOSE RF Ablation System
695T3Leukemia, B-CellOncology4.2754.174.895.691FIT-CD19
696T3Squamous Cell Carcinoma of Head and NeckOncology4.2633.589.460.571AVASOPASEM MANGANESE
697T3Chronic Kidney DiseaseNephrology/Urology4.2615.73101.121MEZAGITAMAB
698T3Hyperphosphatemia due to chronic kidney diseasNephrology/Urology4.2615.73101.121TENAPANOR HYDROCHLORIDE
699T3Metastatic Urothelial CarcinomaOncology4.2516.418.62030ENFORTUMAB VEDOTIN
700T3Mite Infestations4.2552.092.927.672I-LID ’N LASH PRO
701T3rabbit haemorrhagic disease (rabbit)Infectious Disease4.2552.528.251FatrovaxRHD
702T3Multiple stab wounds4.2452258.251Flaminal Hydro
703T3Depressive DisorderPsychiatry4.2315.63101.041BFB-101
704T3Mantle cell lymphoma refractoryOncology4.215.748.452.471CT125A cells
705T3Functional bowel disorderGastroenterology4.1815.299.311.693TRIMEBUTINE
706T3Foot dropNeurology/CNS4.1715.37101.171Fesia Walk
707T3biofilm disease4.1752.527.232StemDetox
708T3Vaginal InfectionsInfectious Disease4.1653.3324.449Clogìn mousse
709T3Adult Myelodysplastic SyndromeHematology4.1513.959.320.591CLOFARABINE
710T3Myelodysplastic SyndromesHematology4.1513.959.320.591Biolevox Neuro
711T3childhood myelodysplastic syndromeOncology4.1513.959.320.591GUADECITABINE
712T3Radiation thrombocytopeniaHematology4.1470.7908.251Thrombosomes
713T3Abdominal and gastrointestinal infectionsImmunology & Inflammation4.1452.571.48.251Meropenem for Injection USP
714T3Biliary painGastroenterology4.1352.9208.251Dolocalma
715T3Atopic disordersImmunology & Inflammation4.1315.359.610.73DUPILUMAB
716T3FracturesCardiovascular4.1370.7808.251CF-M801
717T3Urinary Bladder, Overactive4.1315.638.152.125OXYBUTYNIN
718T3Abrasions4.115228.251CoMatryx OTC
719T3AirwaysImmunology & Inflammation4.115228.251LEVODROPROPIZINE
720T3Atherosclerotic Cardiovascular DiseaseCardiovascular4.115228.251BioMimics 3D Vascular Stent System
721T3Avian infectious bronchitisInfectious Disease4.115228.251Avian Newcastle Disease and Avian Infectious Bronchitis Combined Live Vaccines
722T3Bacterial infection caused by Klebsiella pneumInfectious Disease4.115228.251Compound Cefalexin Capsules
723T3Bacterial infection caused by Streptococcus miInfectious Disease4.115228.251Compound Cefalexin Capsules
724T3Bleeding mild to severe4.115228.251NuStat Flex XR
725T3Bloodstream infectionsInfectious Disease4.115228.251DISQVER
726T3CT of thoracic and lumbar spine4.115228.251KONG®-TL VBR
727T3Carbamylphosphate synthetase deficiencyMetabolic & Endocrine4.115228.251SODIUM PHENYLBUTYRATE
728T3Cardiomyopathy, AlcoholicCardiovascular4.115228.251ACAMPROSATE
729T3Cerebral traumaNeurology/CNS4.115228.251Brecetam Inj.
730T3Cervical disc herniationWomen's & Reproductive Health4.115228.251DiscoGel
731T3Chemotherapy induced peripheral neuropathyNeurology/CNS4.115228.251Rition
732T3Chronic intestinal amoebiasisGastroenterology4.115228.251Axcel Metronidazole
733T3Chronic ischemic heart diseaseCardiovascular4.115228.251Fructose Sodium Diphosphate
734T3Chronic pain due to trauma4.115228.251proff® pain gel
735T3Chronic persistent hepatitisInfectious Disease4.115228.251Liganlong Granules
736T3Complicated infectionInfectious Disease4.115228.251Armillarisin A Injection
737T3Diabetic glomerulopathyMetabolic & Endocrine4.115228.251CALCIUM DOBESILATE
738T3Digestive System Hemorrhage4.115228.251Carbazochrome Sodium Sulfonate for Injection
739T3Digestive problems4.115228.251Egaver
740T3Disease of blood AND/OR blood-forming organ4.115228.251Colla Corii Asini
741T3Diseases of the musculoskeletal system and conMusculoskeletal4.115228.251Traditional Chinese Medicine (TCM) products
742T3Eczematous otitis externaDermatology4.115228.251DermOtic Oil Ear Drops
743T3Egg drop syndromeRare/Genetic4.115228.251Gallimune 302 ND+IB+EDS
744T3Febrile disordersHematology4.115228.251Beijing Tong Ren Tang Angong Niuhuang Wan
745T3Focal lesions, multiple4.115228.251Episealer Talus
746T3Gangrenous disorder4.115228.251EPIFLO
747T3Gonococcal infection (acute) of upper genitourGastroenterology4.115228.251SOMATOSTATIN
748T3Helminthiases4.115228.251Thiaben®
749T3Idiopathic postprandial syndromeRare/Genetic4.115228.251Combizym
750T3ImbalanceGastroenterology4.115228.251Triobiotix 360
751T3Immunoglobulin G deficiencyImmunology & Inflammation4.115228.251Human Immunoglobulin (pH4) for Intravenous Injection, Freeze-dried
752T3Infection by Taenia taeniaeformisInfectious Disease4.115228.251Albel
753T3Inflammatory bone lesionsRare/Genetic4.115228.251Bonopty® Bone Biopsy System
754T3Lactation DisordersDermatology4.115228.251PARNAPARIN SODIUM
755T3Mouth DiseasesImmunology & Inflammation4.115228.251Anginova®
756T3Neoplasms, Post-Traumatic4.115228.251BROMELAINS
757T3Neoplasms, Radiation-Induced4.115228.251CAMISAN
758T3Nickel allergyImmunology & Inflammation4.115228.251Nickel treatment
759T3Oedema due to renal disease4.115228.251Subunit Vaccines against Oedema Disease
760T3Other disorders of synovium and tendonMusculoskeletal4.115228.251OSTENIL® TENDON
761T3Pain in ankle and joints of footMusculoskeletal4.115228.251Zolben®
762T3Partial seizures with secondary generalizationNeurology/CNS4.115228.251LACOSAMIDE
763T3Pododermatitis circumscripta4.115228.251Reacorin
764T3Porcine Reproductive and Respiratory SyndromeRespiratory4.115228.251Rui Lan An
765T3Post-herpetic polyneuropathy4.115228.251ASENAPINE
766T3Postpartum mood disorder4.115228.251Blues Away
767T3Preinfarction syndromeRare/Genetic4.115228.251Troxerutin Tablets
768T3Preventing infection of immunocompromised patiInfectious Disease4.115228.251CEFPIROME
769T3Protozoal diseases4.115228.251MEDAZOL®
770T3Respiratory tract inflammationImmunology & Inflammation4.115228.251Prospan
771T3RhinotracheitisInfectious Disease4.115228.251Jinyu Baoling
772T3Sequelae of disordersNeurology/CNS4.115228.251Pyritinol Hydrochloride Tablets
773T3Skin infections, chronicDermatology4.115228.251BPMatrix
774T3Spinal Enthesopathy, Thoracolumbar Region4.115228.251True Spinal Fixation System
775T3Stabilization4.115228.251GoPLF!
776T3Strangles4.115228.251Strangvac
777T3T cell dysfunction4.115228.251Qu’Ao
778T3Wound Dehiscence4.115228.251ABCcolla® Collagen Membrane
779T3inflammation of the tonsilsImmunology & Inflammation4.115228.251Axetine
780T3meningitis/encephalitisNeurology/CNS4.115228.251QIAstat-Dx Meningitis/Encephalitis Panel
781T3menstruation pain4.115228.251WeWoThom Premium
782T3open wounds4.115228.251Chuangfukang collagen sponge
783T3post traumatic skin infectionDermatology4.115228.251DEBRICHEM
784T3digestive system diseases4.153.224.0610LIPOIC ACID, ALPHA
785T3Metastatic Liver CarcinomaOncology4.0815.491001Edison Histotripsy System
786T3carcinoma of the brainInfectious Disease4.0815.491001Ornidazole Injection
787T3Atopic DermatitisDermatology4.0815.189.611.012ASN008
788T3feline immunodeficiency virus infectionImmunology & Inflammation4.0814.759.71.454Speed Duo FeLV/FIV
789T3infected woundInfectious Disease4.0852255.954Flaminal Hydro
790T3Transfusion dependent anemiaHematology4.0754.142.1656.54IMETELSTAT
791T3DermatosesImmunology & Inflammation4.0653.3308.251Betamethasone Dipropionate Cream
792T3ErosionWomen's & Reproductive Health4.0550.943.118.251Chlorhexidine Acetate Solution
793T3Cystic FibrosisRespiratory4.0412.299.962.021AP-PA02
794T3Cystic fibrosis respiratory infection suppressRespiratory4.0412.299.962.021CMTX-101
795T3Leukodystrophy, MetachromaticMetabolic & Endocrine4.0454.0408.251ATIDARSAGENE AUTOTEMCEL
796T3Clostridium InfectionsInfectious Disease4.0442.084.876.11OG716
797T3Cardiovascular lesions of pintaCardiovascular4.035227.672Spex™ LP
798T3Circulatory Disorders4.035227.232Angipax
799T3Hypervascular lesionOncology4.035227.232Ekobi® Embolization Microspheres
800T3Osteochondral defects4.035227.232TnRhuCartilage
801T3Skin and subcutaneous tissue disordersDermatology4.035227.672Altrazeal®
802T3Cervix uteri cancerOncology4.0223.29101.411Photodynamic Therapy
803T3HBV infectionInfectious Disease4.0214.59.72.212GongMing Anti-HIV Injection
804T3MelanomaOncology4.015.2100.11ENCORAFENIB
805T3Edema due to hypoproteinemiaGastroenterology4.050.773.098.251Torasemide for Injection
806T3Primary MyelofibrosisHematology3.993.53.677.502.852Zilurgisertib x RUXOLITINIB
807T3Advanced MelanomaOncology3.9814.531050.851BI-765063
808T3Bile acid synthesis disorder3.9753.570.67.671CHOLIC ACID
809T3inborn disorder of bile acid synthesisMetabolic & Endocrine3.9753.570.67.231CHOLIC ACID
810T3Meniscus tear3.975226.513StemArt
811T3Periodontal DiseasesOncology3.975226.823NovaBone Porous Granules
812T3Oesophageal squamous cell carcinomaOncology3.9513.82102.631TISLELIZUMAB
813T3Human immunodeficiency virus infectionImmunology & Inflammation3.9514.429.574.21037CABOTEGRAVIR x RILPIVIRINE
814T3Acute tuberculosisNeurology/CNS3.9311.67102.221Sodium Aminosalicylate for Injection
815T3bacterial infectionInfectious Disease3.9314.73100.71CEFIDEROCOL
816T3Other infectious diseases (B99)Infectious Disease3.935226.194Thermostable Single-Shot Vaccines
817T3Advanced breast cancerOncology3.9214.921001Vistusertib (AZD2014)
818T3COVID-19Respiratory3.9214.91100.211VARESPLADIB
819T3Anaplastic thyroid cancerOncology3.9114.88100.521CFT1946
820T3Colorectal cancerOncology3.9114.88100.521BALSTILIMAB
821T3Gastric Hodgkin LymphomaOncology3.9114.61101.491SINTILIMAB
822T3Gastric cancerOncology3.9114.61101.491ZIMBERELIMAB
823T3Alzheimer dementia (AD)Neurology/CNS3.9114.731007RGn530
824T3Leptin ReceptorMetabolic & Endocrine3.8954.430.957.232SETMELANOTIDE
825T3Spinal Degenerative Disorder3.895226.685INERTIA® Deformity Correxxion System
826T3Umbilical cord infectionInfectious Disease3.8852.6608.251CHLORHEXIDINE
827T3Advanced LymphomaOncology3.8212.299.291.051Voxtalisib (SAR245409; XL765)
828T3Pulmonary fibrosis due to recurrent infectionsRespiratory3.8111.249.962.021Meropenem for Injection USP
829T3Edema due to hepatic diseaseGastroenterology3.8151.051.818.251Bumetanide Injection USP
830T3Edema due to renal diseaseNephrology/Urology3.8151.051.818.251Bumetanide Injection USP
831T3HIV-1 infectionInfectious Disease3.7913.778.983.081HIV1/2 antibody detection kits
832T3Partial thickness wound3.7952249Restrata
833T3Mycobacterial infectionsInfectious Disease3.7851.623.658.251PaxView® TB/NTM-ID MPCR-ULFA Ex Kit
834T3Noncancerous tumorsOncology3.785224.8210Sniper® Balloon Occlusion Microcatheter
835T3Posterior Cord SyndromeRare/Genetic3.7450.425.048.251DRX9000
836T3RICKETTSIAL INFECTIONSInfectious Disease3.7251.2525.954Febrile Antigen Kit
837T3Hepatitis C InfectionInfectious Disease3.6513.489.571.761Hepatitis E diagnostic kit
838T3Autoinflammation3.6252.3706.944i.Mune® CD4/CD8
839T3methionine deficiencyMetabolic & Endocrine3.6152.062.088.251Methionine and Vitamin B1 for Injection
840T3Fistulas3.652.4105.495ATZ STEM CELL THERAPY
841T3COVID-19Infectious Disease3.5713.6310026Zofin
842T3Ocular Vascular DisorderCardiovascular3.5215.543.316.11FLUOROMETHOLONE ACETATE
843T3Diaphyseal fracture3.4651.1408.251Point Contact Locking Plate
844T3Pancreatic cancerOncology3.4515.795.1750.451DARATUMUMAB
845T3Lesions in the white matter3.4351.921.28.251Spur® Peripheral Retrievable Scaffold System
846T3Urinary StoneNephrology/Urology3.4350.560.68.251Batugin
847T3Proximal Femoral Fractures3.4520.958.251RoSA - Rotationstable Screw Anchor
848T3No structural defects3.355128.251ProText
849T3Paralysis vocal cordNeurology/CNS3.14502.088.251Silk Voice
850T3Oral mucosal disorder3.1350.4206.823Autologous Cultured Oral Mucosal Epithelium
851T3Bone defectsMusculoskeletal2.9552.7401.8733OsteoXcell VM

Opportunity × crowdedness — where the white-space is

Each scored indication placed by competitive crowdedness (columns, from programme and sponsor counts) against opportunity index (rows). The highlighted top-left cell — high opportunity, few competitors — is the blue-sky white-space corner.

Open (<2.5)
Moderate (2.5–5)
Crowded (5–10)
High (6.5+)
Subacute necrotizing eSkin ulcer due to variHypertension-AssociateProgressive hearing loRare epilepsyExtensively Drug-Resis+35
Drug Abusemitochondrial respiratHigh Grade B-Cell LympPrimary combined hyperTriple hit lymphomaCholestatic hepatitis+18
Locally Recurrent Breagynecologic cancerNUT CarcinomaB Acute Lymphoblastic Hematological neoplasmSystemic Inflammatory
Mid (5–6.5)
Subcutaneous Tissuemuscular dystrophy-dysPolyneuropathy due to Parkinson's disease wiCapillary MalformationAdenovirus Infection+205
Fuchs' endothelial dysResistant hypertensivemonogenic diseaseHand-Foot SyndromeMetastatic Prostatic ATakotsubo syndrome+111
hematopoietic/lymphoidPrematurity of infantLung DiseasesSevere asthmaObstructive cardiomyoppulmonary heart diseas+107
Lower (<5)
Spinal tumorsACTH Syndrome, EctopicGLUT1 Deficiency SyndrIntestinal infections IgE-mediated allergic degenerative brain dis+147
Marburg diseaseAcute respiratory infeRetinal angiopathyVasomotor rhinitisSalmonella infectionChylomicronemia syndro+44
Chronic intestinal faiDiarrhea post chemothedisease of the bloodSquamous Intraepithelifertility disordersCholangiocarcinoma+130

Disease set: every disease in our resolved catalogue of 25,088 that is a high-confidence, auto-resolved concept and carries recorded drug-evidence in our pipeline, after removing exact duplicates, concepts with no named drug asset, and a curated list of non-indication concepts (procedures, bare anatomy and umbrella grouping terms) — 851 indications. No external list is used. Assets are attached to each disease through the resolver's own key (each drug-evidence row's resolved-disease keyword maps to the same resolved concept), not by fuzzy name — so 851 of 851 diseases surface their real programmes. For the treatment-landscape, genetic, tractability and research axes, each disease is also matched to an Open Targets node via every ontology id the resolver holds (primary, canonical, source) with an Open Targets name-search fallback; 492 of 851 resolved to a node. The therapy-gap axis combines Open Targets and our own most-advanced phase; tractability blends Open Targets genetic-association and per-target druggability with our own druggable-genome tier; research is Open Targets literature co-occurrence volume; pipeline momentum reads trial status (advancing vs terminated) from our data; whitespace is a log function of the programme count; prevalence is Orphanet (orphadata product9_prev). Opportunity index computed by us; a research signal, not clinical guidance.